NEXARS
General description
C2P NEXARS is an innovative pharmaceutical and biotechnological SME focused on recombinant therapeutics including vaccines, drug delivery systems, adjuvants and immunostimulating products. The company C2P NEXARS s.r.o. is currently involved in the development and production of immunotherapeutics based on recombinant vaccines, molecular adjuvants and monoclonal antibodies. For its research, the company C2P NEXARS has acquired 2,500 m² of laboratories and production facilities of purity class A/B/C, in which production in the GMP mode and certified analytical methods according to GLP are also being prepared. There is only this operation unit of this kind in the Czech Republic where it would be possible to produce recombinant proteins in eukaryotic expression systems in the GMP regime for the production of vaccines or therapeutics.
Key research infrastructure
- U30 Flow NanoAnalyser
- ZetaSizer Ultra Plus device
- Agilent 1260 Infinity II Bio-MDS liquid chromatograph
- Agilent 6545XT AdvanceBio LC/Q-TOF System liquid chromatograph
- Multifunctional microplate reader NEOALPHAB
- BioRad electrophoretic system (PROTEAN i12 IEF system, Trans-Blot
- Turbo Transfer System, Mini-PROTEAN Tetra Cell) including multifunctional documentation system ChemiDoc ™ MP Imaging System
- Optima XPN-90 BioSafe ultracentrifuge with accessories for protein and nanoparticles purification
- Automated differential scanning calorimetry and isothermal titration equipment
- Leica Stellaris confocal microscope
- Bag bioreactors with control unit for the production of recombinant antigens in eucaryotic expression systems
- FTIR spectrophotometer INVENIO-S Fourier Transform Infrared Spectrometer with TIRF cell and accessories
- spectrophotometer SPECORD S 600 BU
- fully equipped tissue culture laboratory with CO2 incubator CellXpert
- flow box HeraSafe 2030i 1.8. and 5430R and 5920R centrifuges
- Complex system for industrial and laboratory production of liposomes by microfluidic homogenisation and high pressure extrusion
- QuantStudio™ 7 Pro Real-Time PCR.