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Institute of Biotechnology of the Czech Academy of Sciences / BIOCEV
Biotechnology and Biomedicine

Institute of Biotechnology of the Czech Academy of Sciences / BIOCEV

General description


IBT is a research organisation (located in the BIOCEV) focused on excellent basic research in molecular biology with prospective transfer of biotechnological methods and tools to human medicine. The institute has achieved remarkable results, such as the successful development of new diagnostic procedures and vaccines and results in breast cancer treatment MitoTam. IBT´s mission is to focus research on molecular mechanisms of pathologies with considerable impact on population health, to develop new methods of protein engineering and structural biology, to understand the functioning of biological molecular systems and open new ways to modify them.

Key Research Facilities, Infrastructure and Equipment

  • Cell culture and protein expression: biological safety cabinets, refrigerated/dedicated shakers, fermenters, centrifuges, sonicators, Avestin cell disruptor.
  • Protein purification: 5x advanced FPLC systems, state-of-the-art HPLC systems with DAD, fluorescence and MS detectors, bioinert HPLC with UV-VIS, fluorescence and MALLS detection.
  • Enzymology/molecular biology: PCR, agarose gel, SDS-PAGE instruments, documentation systems (LAS4000 CCD, Typhoon 9500), 3x high-end fluorescence/luminescence plate readers.
  • Biophysical equipment: CD spectrometer, Octet platform, Monolith thermophoresis, ITC/DSC calorimeters, Prometheus NT48 DSF, dynamic light scattering, capillary electrophoresis, 4x mass spectrometers, crystallization robots, automated crystallization hotels, X-ray diffractometer, SAXS.
  • Stereomicroscopes, Leica fluorescence stereomicroscope, vibratome, microtome, cryostat, PCR machines.
  • Gene Expression Facility.
  • Sophisticated technologies used in current biomedical research, including animal facility, electron and confocal microscopy, and FACS
  • Imaging with single molecule resolution, super-resolution imaging and optical trapping
  • Czech Centre for Phenogenomics: large research infrastructure unique in combining genetic engineering capabilities, advanced phenotyping and imaging modalities, specific pathogen free (SPF) animal housing and husbandry, as well as cryopreservation and archiving.


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Contact person

Contact us to know more about our location and work environment. Please use the main contact for questions related to administrative matters. Please contact the supervisors/group leaders of respective research groups regarding feasibility of your research proposal with regard to the research group activities.

Your future supervisors

Research groups

The following research groups of this Hosting organisation are involved in the first call of MERIT. The candidates can freely formulate their own research topic aligned with activities and research focus of these research groups.

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2 calls
30 fellowships
30 months