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First Faculty of Medicine, Charles University / BIOCEV
Biotechnology and Biomedicine

First Faculty of Medicine, Charles University / BIOCEV

General description


The laboratory of Medicinal Chemistry of Charles University is located in BIOCEV center. The laboratory focuses on the molecular design, synthesis, separation, characterization and bioanalytical testing of medicinally active organic compounds and their formulations. In terms of medical applications, we focus on theranostics, cellular testing, enzymatic, epigenetic and pharmaceuticals. The molecular design is based on organic compounds based on structural motifs such as hydrazones, methine salts, coumarins, curcumins or Tröger bases. The medicinal potential of the prepared molecules is tested independently or in collaboration with excellent colleagues from the Czech Republic and abroad.

Key Research Facilities, Infrastructure and Equipment

  • NMR Spinsolve (ULTRA 80MHz, Magritec) with 20x sample feeder and flow-through reaction monitoring system. The system allows measurements without deuterated solvent.
  • UV/VIS spectrophotometer SHIMADZU UV-2401
  • Spectrofluorimeter (RF-6000, Shimadzu)
  • Microplate UV/VIS reader SpecraMax®
  • Liquid chromatograph (U)HPLC-SPD/RF/MS (Nexera Shimadzu)
  • Flash/Pure chromatograph
  • Emax High Energy Ball Mill (Retsch)
  • Cryogenic Mill (RETCH)
  • LabScale Reactor 4 L
  • Infrared spectrometer (IRSpirit, Shimadzu)
  • Laser particle size diffraction analyzer (SALD-2300, Shimadzu)


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Contact person

Contact us to know more about our location and work environment. Please use the main contact for questions related to administrative matters. Please contact the supervisors/group leaders of respective research groups regarding feasibility of your research proposal with regard to the research group activities.

Your future supervisors

Research groups

The following research groups of this Hosting organisation are involved in the first call of MERIT. The candidates can freely formulate their own research topic aligned with activities and research focus of these research groups.

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2 calls
30 fellowships
30 months